Low Frequency BOLD Fluctuations and Brain Functional Connectivity

نویسنده

  • Vesa Kiviniemi
چکیده

Functional connectivity refers to correlations between spatially remote neurophysiological events as described by Friston & Büchel. Functional connectivity is simply a statement about the observed correlations and does not imply how the correlation is mediated. Effective connectivity is closer to inter-neuronal connectivity as it refers to influence that one neuronal system exerts over another (Friston & Büchel). The difference between functional and effective connectivity is related to differences in the time and scale of the measurements; e.g. hemodynamics response function vs. spike trains. The following text focuses on the relationship between functional connectivity and low frequency fluctuations detected in resting state brain activity with BOLD fMRI.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Loss of Coherence of Low Frequency Fluctuations of BOLD FMRI in Visual Cortex of Healthy Aged Subjects

Aging effects on blood-oxygen-level-dependent (BOLD) functional MRI (fMRI) have been studied using task induced hemodynamic responses with controversial findings. The present study systematically investigated the normal aging effect in the visual cortex using 3 indices of low frequency fluctuations of resting state BOLD fMRI, i.e., amplitude of low frequency fluctuations (ALFF), regional homoge...

متن کامل

Age effects on low frequency physiological fluctuations in resting BOLD fMRI

Introduction: Studies have shown that low frequency temporal components (<0.1Hz) in resting state BOLD fMRI reflect spontaneous fluctuations of brain physiology and metabolism, which form the basis for the widely adopted “functional connectivity” analysis to characterize the resting state using BOLD fMRI[1]. Studies also found significant linear correlations between activation induced BOLD sign...

متن کامل

Spontaneous low-frequency blood oxygenation level-dependent fluctuations and functional connectivity analysis of the 'resting' brain.

Functional magnetic resonance imaging techniques using the blood oxygenation level-dependent (BOLD) contrast are widely used to map human brain function by relating local hemodynamic responses to neuronal stimuli compared to control conditions. There is increasing interest in spontaneous cerebral BOLD fluctuations that are prominent in the low-frequency range (<0.1 Hz) and show intriguing spati...

متن کامل

Resting state functional connectivity in the human spinal cord

Functional magnetic resonance imaging using blood oxygenation level dependent (BOLD) contrast is well established as one of the most powerful methods for mapping human brain function. Numerous studies have measured how low-frequency BOLD signal fluctuations from the brain are correlated between voxels in a resting state, and have exploited these signals to infer functional connectivity within s...

متن کامل

Dependence of Low Frequency Functional Connectivity

Resting state low frequency (<0.08 Hz) fluctuations in MR timecourses that are temporally correlated between functionally related areas have been observed in recent studies. These fluctuations have been assumed to arise from spontaneous blood oxygenation level-dependent (BOLD) oscillations. This work examines the T*2 characteristics of the low frequency fluctuations (functional connectivity) an...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006